Molecular Neurodegeneration

Moore Laboratory
The Moore Laboratory investigates the molecular pathophysiology of Parkinson’s disease, a chronic progressive
neurodegenerative movement disorder.

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Recent Publications

Nguyen APT et al. Pre-print. Dopaminergic neurodegeneration induced by Parkinson’s disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity. bioRxiv.

Beilina A et al. 2020. The Parkinson’s disease protein LRRK2 interacts with the GARP complex to promote retrograde transport to the trans-Golgi network. Cell Rep.

Cunningham LA, Moore DJ. 2020. Endosomal sorting pathways in the pathogenesis of Parkinson’s disease. Prog Brain Res.

Patterson JR et al. Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils. Neurobiol Dis.

Join Our Team

We are continually seeking highly motivated individuals with a strong publication record to join our energetic and fast-paced lab as postdoctoral fellows. A Ph.D. with molecular and cellular biology or neuroscience experience is required to apply. Additional experience in biochemistry, proteomics, microscopy, viral vector technology, neuropathology and/or behavioral assays is preferred (but not necessary). Interested candidates should email Dr. Moore to inquire. Graduate students interested in joining the lab are encouraged to apply through Van Andel Institute Graduate School (VAIGS).